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Co-administration of Anastrozole with other drugs such as Antipyrine and Cimetidine is unlikely to result in clinically significant drug interactions mediated by cytochrome P450.
Oestrogen-containing therapies should not be co-administered with Anastrozole as they would negate its pharmacological action.
Tamoxifen and/or other therapies containing oestrogen should not be co-administered with Anastrozole, as they may diminish its pharmacological action (see Contraindications).
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