Zadaxin Dosage/Direction for Use

Zadaxin is intended for SC injection and should not be given IV. It should be reconstituted with 1 mL of the diluent provided, which consists of 1 mL Sterile Water for Injection, immediately prior to use. At the discretion of the physician, the patient may be taught to self-administer the medication.
Chronic Hepatitis B: The recommended dose of Zadaxin for the treatment of chronic hepatitis B is 1.6 mg administered SC twice a week with doses separated by 3 or 4 days. Therapy should be continued for 6 months (52 doses) without interruption.
Vaccine Adjuvant: The recommended dose of Zadaxin when used as an enhancement to viral vaccines is 900 mcg/m² (1.6 mg) administered SC twice a week with doses separated by 3 or 4 days and the 1st dose given coincident with the vaccine. Therapy should be continued for 4 weeks (a total of 8 doses) after a single-dose vaccine immunization regimen. For a multidose vaccine immunization regimen, therapy should continue twice a week between vaccinations and for 3 weeks (a total of 5-6 doses) after the last vaccination.