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The dosage schemes given are usually satisfactory, but regular examination of the blood is advisable. If megaloblastic anaemia fails to respond to Cyanocobalamin Injection, folate metabolism should be investigated.
Doses in excess of 10 micrograms daily may produce a haematological response in patients with folate deficiency.
Indiscriminate administration may mask the true diagnosis. Cardiac arrhythmias secondary to hypokalaemia during initial therapy have been reported. Plasma potassium should therefore be monitored during this period.
