MMR II Description

M-M-R II vaccine is a sterile lyophilized preparation of (1) Measles Virus Vaccine Live, an attenuated line of measles virus, derived from Enders' attenuated Edmonston strain and propagated in chick embryo cell culture; (2) Mumps Virus Vaccine Live, the Jeryl Lynn (B level) strain of mumps virus propagated in chick embryo cell culture; and (3) Rubella Virus Vaccine Live, the Wistar RA 27/3 strain of live attenuated rubella virus propagated in WI-38 human diploid lung fibroblasts. The cells, virus pools, recombinant human serum albumin and fetal bovine serum used in manufacturing are tested and determined to be free of adventitious agents.
After reconstitution, each 0.5 mL dose contains not less than 3.0 log₁₀ TCID₅₀ (tissue culture infectious doses) of measles virus; 4.1 log₁₀ TCID₅₀ of mumps virus; and 3.0 log₁₀ TCID₅₀ of rubella virus.
Excipients/Inactive Ingredients: Each dose is calculated to contain sorbitol (14.5 mg), sucrose (1.9 mg), porcine hydrolyzed gelatin (14.5 mg), recombinant human albumin (≤0.3 mg), approximately 25 mcg of neomycin and other buffer and media ingredients. The product contains no preservative.