Lastet Adverse Reactions

Hematologic: Such symptoms as pancytopenia, leukopenia, thrombocytopenia, hemorrhage, anemia, may occur.
Hepatic: Abnormalities in hepatic function such as the elevations of GOT, GPT, Al-P, bilirubin levels may occur. Also elevations of γ-GTP, LDH levels may occur infrequently.
Renal: Such symptoms as elevations of BUN and creatinine levels, may occur. Also urinary protein positive may occur infrequently.
Respiratory: Interstitial pneumonia may occur.
Gastrointestinal: Such symptoms as nausea, vomiting, anorexia, stomatitis, diarrhea, abdominal pain, constipation, may occur.
Hypersensitivity: Such symptoms as rash may occur.
Dermatologic: Such symptoms as serious alopecia, and erythema and pruritus, may occur. Also pigmentation, etc. may occur infrequently.
Psychoneurologic: Peripheral neuropathy such as numbness of the limbs and headaches, etc. may occur.
Cardiovascular: Such symptoms as abnormal electrocardiograms, arrhythmia, tachycardia and hypotension, may occur infrequently.
Electrolytes: Electrolyte abnormalities such as sodium, potassium, chlorine, calcium may appear.
Others: Such symptoms as malaise and fever, may occur. Also hot facial flushes, edema, decreased serum total protein levels may occur infrequently.