Safety in the treatment of infections during pregnancy has not been established If administration to pregnant patients is considered necessary, its potential benefits should be weighed against the possible hazards to the foetus. There is evidence to suggest that the drug can penetrate the placental barrier and be detected in the milk of nursing mothers. Safety of Sodium Fusidate for the treatment of infections in women who are breast feeding has not been established. Corticosteroid applied to the skin can be absorbed in sufficient amounts to produce systemic effects. Special care must be taken when giving to paediatric patients as systemic absorption can occur in topical administration causing growth retardation. Thus, suitable precautions should also be taken when treating stasis dermatitis and other skin diseases with impaired circulation. Long-term continuous topical therapy should be avoided.
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