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It must be noted that bronchospasm can result in aerosol therapy with acetylcysteine in patients with a hypersensitive bronchial system (eg, asthmatics). Therefore, the simultaneous use of a bronchodilator is recommended for aerosol therapy.
Rarely, acetylcysteine can induce rhinitis and stomatitis. In very rare instances, allergic reactions (itching, urticaria and exanthema) have also been reported.
