Use in Pregnancy: Etoposide can cause fetal harm when administered to a pregnant woman. There are no adequate and well-controlled studies in pregnant women. If this drug is used during pregnancy, or if the patient becomes pregnant while receiving this drug, she should be apprised of the potential hazard to the fetus. Women of childbearing potential should not be started on etoposide until pregnancy has been ruled out and should be fully counseled on the serious risk to the fetus should they become pregnant while undergoing treatment.
Use in Breastfeeding: It is not known whether this drug is excreted in breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or the drug, taking into account the importance of the drug to the mother.