Divator Drug Interactions

There are some medicines that may interact with DIVATOR, these are: Medicines used to modulate immune response, e.g. cyclosporin or antihistamines such as terfenadine, astemizole.
Macrolide antibiotics, e.g. erythromycin; azole antifungal medicines, e.g. ketoconazole, itraconazole; rifampicin (an antibiotic).
Medicines to regulate lipid levels, e.g. fibric acid derivatives, niacin, colestipol.
Some calcium channel blockers used for angina or high blood pressure, e.g. nifedipine; some benzodiazepines used for anxiety and other conditions, e.g. diazepam; medicines to regulate heart rhythm.
Protease inhibitors used in the treatment of HIV e.g. nelfinavir.
Digoxin, warfarin, oral contraceptives, antacids, phenytoin (an anti-convulsant for epilepsy).
Co-administration of strong CYP3A4 inhibitors (e.g. ciclosporin, telithromycin, clarithromycin, delavirdine, stiripentol, ketoconazole, voriconazole, itraconazole, posaconazole and HIV protease inhibitors including ritonavir, lopinavir, atazanavir, indinavir, darunavir, etc.) should be avoided if possible. In cases where co-administration of these medicinal products with atorvastatin cannot be avoided, lower starting and maximum doses of atorvastatin should be considered and appropriate clinical monitoring of the patient is recommended.
In patients taking telaprevir, concomitant use of atorvastatin should be avoided.
The dose of atorvastatin should not exceed 40 mg daily when taking with boceprevir and close clinical monitoring is recommended.
When taking DIVATOR, do not drink more than one or two small glasses of grapefruit juice per day.
It is important to tell the doctor about all the medicines being taken, including those that have been bought without a prescription.