Apo-Duloxetine Drug Interactions

Some medicines may interact with duloxetine. These include: Monoamine oxidase inhibitors (MAOIs), medicines used to treat some types of depression. The patient must stop taking MAOIs at least two weeks before starting duloxetine. The patient must stop taking duloxetine at least 5 days before he/she starts taking a MAOI.
Other medicines used to treat depression, panic disorder, anxiety or obsessive illnesses, including tryptophan.
Strong painkillers such as tramadol, pethidine.
A type of migraine treatment called 'triptans', such as sumatriptan or zolmitriptan.
Medicines used to treat stress urinary incontinence such as tolteridone.
Medicines used to treat heart problems such as flecainide or propafenone.
Thioridazine, a medicine used to treat schizophrenia.
Herbal medicines such as St John's Wort (Hypericum perforatum).
Warfarin, a medicine used to thin the blood (anticoagulant).
If the patient is taking any of these he/she may need a different dose or he/she may need to take different medicines.
Other medicines not previously listed may also interact with duloxetine.