Hypersensitivity. Presence or history of liver disease. Concomitant use w/ MAOIs or taking MAOIs w/in the last 14 days. Concomitant use w/ potent CYP1A2 inhibitor eg, fluvoxamine or ciprofloxacin.
Allergies to any other medicines or substances eg, foods, preservatives, dyes. Presence or history of any medical conditions especially glaucoma, high BP, heart problems, kidney problems, history of seizures, DM. Patient or family history of bipolar disorder, depression or suicide. Surgery or anaesth. Currently receiving or planned dental treatment. Alcohol consumption. Do not start treatment in patient receiving linezolid; wait until 24 hr after last dose of linezolid before starting duloxetine treatment. Stop taking duloxetine at least 5 days before starting a MAOI. Monitor for any signs of suicidal thoughts or other mental/mood changes. Monitor for signs of liver damage. May impair ability to drive & use machines. Pregnancy & lactation. Should not be used in childn & adolescents <18 yr.
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