Tablet: Should be used with caution in patients with a history of allergic reactions. In patients with severely impaired liver or renal function the dose should be adequately reduced or the dosing interval prolonged.
Powder for oral suspension: Hypersensitivity reactions, including anaphylaxis.
Prolonged use may result in fungal or bacterial superinfection.
In patients with renal impairment, doses and/or frequency of administration should be modified in response to the degree of renal impairment.
High percentage of patients with infectious mononucleosis have developed rash during therapy, ampicillin-class antibiotics not recommended in these patients.
Incidence of diarrhea of amoxicillin/clavulanic acid is higher than with amoxicillin alone. Due to differing content of clavulanic acid, not all formulations are interchangeable.
Low incidence of cross-allergy with cephalosporins exists.