Vyndamax: Side Effects & Dosing

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing

Concise Prescribing Info

Contents

Tafamidis

Indications/Uses

Wild-type or hereditary transthyretin amyloidosis in adults w/ cardiomyopathy.

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Dosage/Direction for Use

1 cap once daily.

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Overdosage

View Vyndamax overdosage for action to be taken in the event of an overdose.

Administration

May be taken with or without food: Swallow whole, do not crush/cut.

Contraindications

Hypersensitivity.

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Special Precautions

Discontinue use in patients who undergo organ transplantation. Patients w/ NYHA Class IV. Increased LFTs & decreased thyroxine. Monitor patients & assess need for other therapy, including organ transplantation. Contains ≤44 mg sorbitol in each cap. Concomitant use w/ or dietary intake of products containing sorbitol (or fructose). Severe renal (CrCl ≤30 mL/min) & hepatic impairment. Women of childbearing potential should use appropriate contraception during & for 1 mth after stopping treatment. Not recommended during pregnancy & in women of childbearing potential not using contraception. Not to be used during lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Flatulence, increased LFT. Diarrhoea; rash, pruritus.

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Drug Interactions

Inhibition of efflux transporter BCRP & increased systemic exposure of BCRP substrates eg, MTX, rosuvastatin, imatinib. Decreased serum conc of total thyroxine w/o accompanying change in free thyroxine (T₄) or TSH.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Vyndamax detailed prescribing information

Storage

View Vyndamax storage conditions for details to ensure optimal shelf-life.

Description

View Vyndamax description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Other Cardiovascular Drugs

ATC Classification

N07XX08 - tafamidis ; Belongs to the class of other nervous system drugs.

Thai FDA Category

Presentation/Packing

Form

Vyndamax soft-gelatin cap 61 mg

Packing/Price

3 × 10's

Vyndamax

tafamidis

Manufacturer:

Pfizer

Distributor:

Zuellig Pharma

Marketer:

Pfizer