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Pregnancy: Pravastatin sodium is contraindicated in pregnant females or those who may become pregnant. Pravastatin sodium was found to cross the placenta. Cholesterol biosynthesis may be important in fetal development. Serum cholesterol and triglycerides increase normally during pregnancy. The discontinuation of lipid lowering medications temporarily during pregnancy is not expected to have significant impact on the long term outcomes of primary hypercholesterolemia treatment. Pravastatin sodium should be discontinued immediately if an unplanned pregnancy occurs during treatment. Adequate contraception is recommended if an HMG-CoA reductase inhibitor is required in females of reproductive potential. Females planning a pregnancy should discontinue the HMG-CoA reductase inhibitor 1 to 2 months prior to attempting to conceive.
Breastfeeding: Use of Pravastatin sodium in breastfeeding women is contraindicated. A small amount of Pravastatin sodium is present in breast milk.
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