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Hypercholesterolaemia: Treatment of primary hypercholesterolaemia or mixed dyslipidaemia, as an adjunct to diet, when response to diet and other non-pharmacological treatments (eg. exercise, weight reduction) is inadequate.
Primary prevention: Reduction of cardiovascular mortality and morbidity in patients with moderate or severe hypercholesterolaemia and at high risk of a first cardiovascular event, as an adjunct to diet.
Secondary prevention: Reduction of cardiovascular mortality and morbidity (myocardial infarction, revascularization, ischemic stroke and transient ischemic attack) in patients with a history of myocardial infarction or unstable angina pectoris and with either normal or increased cholesterol levels, as an adjunct to correction of other risk factors.
Post-transplantation: Reduction of post-transplantation hyperlipidaemia in patients receiving immunosuppressive therapy following solid-organ transplantation.
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