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Ascorbic acid should be given with care to patients with underlying renal failure due to the risk of formation of renal oxalate calculi. Tolerance may be induced in patients taking high doses.
Large doses of Ascorbic Acid have resulted in haemolysis in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Effects on ability to drive and use machines: Ascorbic acid injection is unlikely to affect the patient's ability to drive or use machinery.
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