Vitamin C Injection T P: Side Effects & Dosing

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing

Concise Prescribing Info

Contents

Ascorbic acid

Indications/Uses

Treatment & prevention of scurvy, or other conditions requiring vit C supplementation, where deficiency is acute or PO is difficult.

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Dosage/Direction for Use

IM/IV Adult Treatment of scurvy 0.5-1 g daily. Prevention of scurvy 200-500 mg daily. Childn Curative purpose: 100-300 mg daily. Protective treatment: 30 mg daily.

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Overdosage

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Contraindications

Hyperoxaluria.

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Special Precautions

Not to be given in patients w/ normal cardiac function for the 1st mth after starting desferrioxamine. May induce tolerance w/ high doses. Haemolysis in patients w/ G6PD deficiency w/ large doses. Risk of renal oxalate calculi formation in patients w/ underlying renal failure. Not to be given in conjunction w/ desferrioxamine in patients w/ cardiac dysfunction. Not to take >1 g daily during pregnancy. Lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

GI disorders including diarrhoea; hyperoxaluria & formation of renal oxalate calculi if urine becomes acidic; deficiency symptoms.

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Drug Interactions

Concomitant use w/ drugs that induce tissue desaturation of ascorbic acid eg, aspirin, nicotine from cigarettes, alcohol, several appetite suppressants, Fe, phenytoin, some anticonvulsants, oestrogen component of OCs & tetracycline. Unexpected renal tubular reabsorption of acidic drugs in large doses. Decreased reabsorption & therapeutic effect w/ basic drugs. Reduced response to oral anticoagulants in large doses. Decreased fluphenazine plasma conc. Interference w/ numerous lab tests based on oxidation-reduction reactions. May worsen Fe toxicity w/ desferrioxamine in patients w/ Fe overload. Reduced absorption & decreased urinary excretion w/ aspirin. Development of potentially fatal encephalopathy w/ Al antacids & oral citrate. Lower serum levels w/ OCs.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Vitamin C Injection T P detailed prescribing information

Storage

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Description

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Action

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MIMS Class

Vitamin C

ATC Classification

A11GA01 - ascorbic acid (vit C) ; Belongs to the class of ascorbic acid (vitamin C). Used as dietary supplements.

Thai FDA Category

Presentation/Packing

Form

Vitamin C Injection T P soln for inj 500 mg/2 mL

Packing/Price

100 mL x 1's;2 mL x 50 × 1's

Vitamin C Injection T P

ascorbic acid

Manufacturer:

T. P. Drug

Distributor:

T. P. Drug