Vilerm Adverse Reactions

Undesirable effects from the use of Acyclovir may occur: Central nervous system (CNS): Aggressive behavior, agitation, ataxia, coma, confusion, decreased consciousness, delirium, dizziness, encephalopathy, hallucinations, obtundation, paresthesia, psychosis, seizures, somnolence, tremor. These symptoms are often found in patients with renal impairment and in older adults.
Gastrointestinal: Nausea, vomiting, diarrhea, gastrointestinal distress.
Hematologic: Anemia, hemolysis, leukocytoclastic vasculitis, leukocytosis, leukopenia, lymphadenopathy, neutrophilia, thrombocytosis, thrombocytopenia.
Dermatologic and hypersensitivity reactions: Rash, pruritus, urticaria, Stevens-Johnson syndrome.
Renal: Increased BUN and/or serum creatinine concentration, renal failure/anuria, hematuria.
Miscellaneous: Fever.
Tablet: Central nervous system (CNS): Dysarthria, headache, malaise.
Hematologic: Thrombotic thrombocytopenic purpura, hemolytic uremia syndrome.
Dermatologic and hypersensitivity reactions: Alopecia, angioedema, anaphylaxis, erythema multiforme, photosensitivity rash, toxic epidermal necrolysis.
Hepatic: Elevated liver function test results, hepatitis, hyperbilirubinemia, jaundice.
Miscellaneous: Pain.
Rare but important or life-threatening: Hypotension, myalgia, peripheral edema, thirst, visual abnormalities.
Powder for infusion: Local effects: When given intravenously it may cause local reaction at the injection site with inflammation, phlebitis and tissue necrosis.
Renal effects: Abnormal urinalysis.
In case of rapid administration, transient increases in BUN and serum creatinine concentrations. Renal failure occurred especially in patients with dehydration or used Acyclovir concomitantly with other nephrotoxic drugs.
GI effects: Anorexia.
Hematological effects: Disseminated intravascular coagulation, hemoglobinemia, neutropenia.
Others: Liver dysfunction, hepatitis, jaundice, hypotension, myalgia, peripheral edema, thirst, visual abnormalities.