Sign Out
500 mg: Symptoms include acute renal failure and seizures. Treatment should include GI decontamination and supportive care. Levofloxacin cannot be removed by peritoneal or hemodialysis.
750 mg: Overdose and Treatment: According to toxicity studies in animals, the most important signs to be expected following acute overdosage of Levofloxacin 750 mg are central nervous system symptoms such as confusion, dizziness, impairment of consciousness, and convulsive seizures, as well as gastrointestinal reactions such as nausea and mucosal erosions.
In the event of an acute overdosage, the stomach should be emptied. Antacid may be used for protection of gastric mucosa. No specific antidote exists. The patient should be observed and appropriate hydration maintained. Levofloxacin is not efficiently removed by hemodialysis or peritoneal dialysis.
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