Trexan Contraindications

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing Local Product Insert

The information highlighted (if any) are the most recent updates for this brand.

Full Prescribing Info

Contraindications

Significantly impaired hepatic function; Significantly impaired renal function (creatinine clearance less than 30 ml/min) for methotrexate doses <100 mg/m², and moderate renal impairment (creatinine clearance less than 60 ml/min) for methotrexate doses >100 mg/m² (see Dosage & Administration); Pre-existing blood dyscrasias, such as bone marrow hypoplasia, leukopenia, thrombocytopenia or significant anaemia; Alcoholism; Severe acute or chronic infections and immunodeficiency syndrome; Stomatitis, ulcers of the oral cavity and known active gastrointestinal ulcer disease; Pregnancy and breast-feeding (see Use in Pregnancy & Lactation); Hypersensitivity to methotrexate or to any of the excipients listed in Description; During methotrexate therapy concurrent vaccination with live vaccines must not be carried out; Methotrexate should not be used concomitantly with drugs with antifolate properties (e.g. co-trimoxazole) (see Interactions).

Trexan Contraindications

methotrexate

Manufacturer:

Orion Pharma Thai

Distributor:

Zuellig Pharma

Marketer:

Orion Pharma Thai