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Overdose of ticagrelor may affect to gastrointestinal bleeding and significant adverse drug reactions should be monitored e.g. dyspnoea and ventricular pauses which has to be immediately rescued.
In the event of an overdose, observe for these potential adverse effects and consider ECG monitoring.
There is currently no known antidote to reverse the effects of ticagrelor, and ticagrelor is not expected to dialyzable. Treatment of overdose should follow standard medical practice. The expected effect of excessive ticagrelor dosing is prolonged duration of bleeding risk associated with platelet inhibition. If bleeding occurs appropriate supportive measures should be taken.
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