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Pregnancy: Glibenclamide crosses the placenta. Use of Glibenclamide in pregnant women should generally be avoided because of the risk of neonatal hypoglycemia. Women with type 2 diabetes who planning a pregnancy or during pregnancy should be treated with insulin.
Lactation: Glibenclamide may be present in breast milk. Because of the potential for hypoglycemia in the breastfeeding infant, a decision should be made whether to discontinue breastfeeding or to discontinue the drug, taking into account the importance of treatment to the mother. If Glibenclamide is discontinued, administration of insulin should be considered.
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