Silatio Adverse Reactions

Based upon normal doses for either indication or route. (Adverse effects such as flushing, diarrhea, myalgia, and visual disturbances may be increased with dose >100 mg/24 hours.)
Cardiovascular: Flushing.
Central nervous system: Dizziness, headache, insomnia, paresthesia.
Dermatologic: Erythema, skin rash.
Gastrointestinal: Diarrhea, dyspepsia, gastritis, nausea.
Genitourinary: Urinary tract infection.
Hepatic: Increased liver enzymes.
Neuromuscular & skeletal: Back pain, Myalgia.
Ocular: Visual disturbance (including vision color change, blurred vision, and photophobia).
Respiratory: Epistaxis, exacerbation of dyspnea, nasal congestion, rhinitis, sinusitis.
Miscellaneous: Fever.
Rare but important or life-threatening: Abnormal hepatic function tests, absent reflexes, amnesia (transient global),anemia, anorgasmia, anterior chamber eye hemorrhage, anterior ischemic optic neuropathy, arthritis, auditory impairment, basal cell carcinoma, breast hypertrophy, burning sensation of eyes, cardiac failure, cataract, cerebrovascular hemorrhage, colitis, cystitis, depression, diaphoresis, diplopia, dry eye syndrome, dysphagia, ECG abnormality, ejaculatory disorder, exfoliative dermatitis, falling, gastroenteritis, genital edema, gingivitis, glossitis, gout, herpes simplex infection, hyperglycemia, hypernatremia, hypersensitivity reaction, hypertension, hypertonia, hypoglycemia, increased bronchial secretions, increased intraocular pressure, ischemic heart disease, laryngitis, leukopenia, malignant melanoma, migraine, myasthenia, mydriasis, myocardial infarction, neuralgia, neuropathy, orthostatic hypotension, otalgia, peripheral edema, pharyngitis, photophobia, priapism, prolonged erection, pulmonary hemorrhage, rectal hemorrhage, retinal edema, retina hemorrhage, retinal vascular disease, rupture of tendon, seizure, severe sickle cell crisis (vaso-occlusive crisis in patients with pulmonary hypertension associated with sickle cell disease), skin photosensitivity, stomatitis, syncope, synovitis, tachycardia, transient ischemic attacks, unstable diabetes, urinary incontinence, ventricular arrhythmia, vitreous detachment, vitreous traction.