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Common adverse effects reported in patients receiving oral Sumatriptan for the treatment of migraine include malaise or fatigue, nausea or vomiting (however, nausea and vomiting also are symptoms associated with migraine attacks and/or the postdromal period, and it may be difficult to distinguish the effects or underlying disease processes from drug-induced effects), dizziness or vertigo, tingling, nasal discomfort, atypical sensation and sensations of pain, heaviness, pressure or tightness.
Serious adverse events that have been reported rarely including coronary artery vasospasm, transient myocardial ischemia, myocardial infarction, ventricular tachycardia, ventricular fibrillation, stroke, subarachnoid hemorrhage. (See table.)
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