Sevorane Dosage/Direction for Use

Premedication: Premedication should be selected according to the need of the individual patient and at the discretion of the anesthesiologist.
Surgical Anesthesia: The concentration of sevoflurane being delivered from a vaporizer during anesthesia should be known. This may be accomplished by using a vaporizer calibrated specifically for sevoflurane.
Induction: Dosage should be individualized and titrated to the desired effect according to the patient's age and clinical status. A short-acting barbiturate or other IV induction agent may be administered, followed by inhalation of sevoflurane. Induction with sevoflurane may be achieved in oxygen or in combination with oxygen-nitrous oxide mixtures. In adults, inspired concentrations of up to 5% sevoflurane usually produce surgical anesthesia in <2 min. In children, inspired concentrations of up to 7% sevoflurane usually produce surgical anesthesia in <2 min.
Maintenance: Surgical levels of anesthesia may be sustained with concentrations of 0.5-3% sevoflurane with or without the concomitant use of nitrous oxide. (See Table 2.)

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Emergence: Emergence times are generally short following sevoflurane anesthesia. Therefore, patients may require postoperative pain relief earlier.