Setin Special Precautions

Precaution is recommended when Cetirizine concomitant use with alcohol.
Patients should be warned that additive CNS depressants may occur when Cetirizine is administered concomitantly with other CNS depressants (e.g., alcohol, sedatives, tranquilizers) and should be advised to avoid such concomitant use.
Use with caution in patients with predisposing factors of urinary retention (e.g., spinal cord lesion, prostatic hyperplasia), as Cetirizine may increase the risk of urinary retention.
Caution in epileptic patients and patients at risk of convulsion is recommended.
Pruritus and/or urticaria may occur when Cetirizine is stopped, even if those symptoms were not present before treatment initiation. In some cases, the symptoms may be intense and may require treatment to be restarted. The symptoms should resolve when the treatment is restarted.
Use antihistamines with caution in patients with narrow-angle glaucoma, renal impairment, hepatic impairment, stenosing peptic ulcer, pyloroduodenal obstruction, symptomatic prostatic hypertrophy, bronchial asthma, increased intraocular pressure, thyroid dysfunction, cardiovascular disease, and hypertension.
Effect on ability to drive and use machine: Objective measurement of driving ability, sleep latency and assembly line performance have not demonstrated any clinically relevant effects at the recommended dose 10 mg.
However, patients who experience somnolence should refrain from driving, engaging in potentially hazardous activities or operating machinery.
Patients intending to drive, engaging in potentially hazardous activities or operating machinery should not exceed the recommended dose and should take their response to the medicinal product into account.