Setin Dosage/Direction for Use

Tablets: Children aged from 6 to 12 years: Half of the tablet (5 mg) twice daily.
Adults and children above 12 years of age: 1 tablet (10 mg) once daily.
A half of the tablet starting dose (5 mg) may be proposed in adults if this leads to satisfactory control of the symptoms.
Solution: Children aged from 2 to 6 years: 2.5 mL of oral solution (2.5 mg) twice daily.
Children aged from 6 to 12 years: 5 mL of oral solution (5 mg) twice daily.
Adults and children over 12 years of age: 10 mL of oral solution (10 mg) once daily.
A 5 mL starting dose (5 mg) may be proposed in adults if this leads to satisfactory control of the symptoms.
Elderly: Data does not suggest that the dose needs to be reduced in elderly subjects provided that the renal function is normal.
Renal impairment: Since Cetirizine is mainly excreted via renal route, in cases no alternative treatment can be used, the dosing intervals must be individualized according to renal function. Refer to table. (See table.)

Click on icon to see table/diagram/image

In paediatric patients suffering from renal impairment, the dose will have to be adjusted on an individual basis taking into account the renal clearance, age and body weight of the patient.
Hepatic impairment: No dose adjustment is needed in patients with solely hepatic impairment.
Patients with hepatic impairment and renal impairment: Dose adjustment is recommended following "Renal impairment" as previously mentioned.