Selexa Overdosage

Overdose: 200 mg: There is no clinical experience of overdose. Single dose up to 1,200 mg and multiple doses up to 1,200 mg twice daily have been administered to healthy subjects for nine days without clinically significant adverse effects. In the event of suspected overdose, appropriate supportive medical care should be provided. Dialysis is unlikely to be an efficient method of medicinal product removal due to high protein binding.
400 mg: Overdosage of NSAIDs can cause lethargy, drowsiness, nausea, vomiting and epigastric pain; these manifestations generally are reversible with supportive care. GI bleeding also has been reported. Rarely, hypertension, acute renal failure, respiratory depression and coma may occur. Anaphylactoid reactions have been reported with therapeutic use of NSAIDs and may occur following an overdosage.
Treatment: 400 mg: Treatment of NSAIDs overdosage involves symptomatic and supportive care; there is no specific antidote for NSAIDs overdosage. During the first 4 hours after overdosage, emesis and/or administration of activated charcoal (60-100 g in adults) and/or osmotic cathartic may be useful in symptomatic patients or in those who reportedly ingested a large overdosage.