Selexa Contraindications

Hypersensitivity to the active substance or to any of the excipients listed in Description.
Known hypersensitivity to sulfonamides.
Active peptic ulceration or gastrointestinal (GI) bleeding.
Patients who have experienced asthma, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria or other allergic-type reaction after taking acetylsalicylic acid (aspirin) or other non-steroidal anti-inflammatory drugs (NSAIDs) including COX-2 inhibitors.
Severe hepatic dysfunction (serum albumin <25 g/l or Child-Pugh score ≥10).
Patients with estimated creatinine clearance <30 ml/min.
Inflammatory bowel disease.
Congestive heart failure (NYHA II-IV).
Established ischaemic heart disease, peripheral arterial disease and/or cerebrovascular disease.
Celecoxib is contraindicated for the treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery.
Use in Pregnancy & Lactation: In pregnancy and in women of childbearing potential unless using an effective method of contraception (see Use in Pregnancy & Lactation).
Celecoxib has been shown to cause malformations in the two animal species studied (see Use in Pregnancy & Lactation and Pharmacology: Toxicology: Preclinical safety data under Actions). The potential for human risk in pregnancy is unknown, but cannot be excluded.
Breast-feeding (see Use in Pregnancy & Lactation and Pharmacology: Toxicology: Preclinical safety data under Actions).