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Concomitant administration of Cefdinir and antacid reduces the Cefdinir absorption. If antacid is required during Cefdinir therapy, Cefdinir should be taken at least 2 hours before or after antacid.
Concomitant administration of Cefdinir and therapeutic iron supplement reduces the Cefdinir absorption. If therapeutic iron supplement is required during Cefdinir therapy, Cefdinir should be taken at least 2 hours before or after the therapeutic iron supplement. Red stools is observed in infants given Cefdinir while being fed with infant formula containing therapeutic iron supplement. It was considered important to be aware of the interaction because of the risk being mistaken as a sign of gastrointestinal bleeding.
Concomitant administration of Cefdinir and probenecid increases the Cefdinir plasma level and prolonged elimination half-life.
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