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Salagen

Salagen Overdosage

pilocarpine

Manufacturer:

Eisai

Distributor:

DKSH
Full Prescribing Info
Overdosage
Fatal overdosage with pilocarpine has been reported in the scientific literature at doses presumed to be >100 mg in 2 hospitalized patients, pilocarpine 100 mg is considered potentially fatal. Overdosage should be treated with atropine titration (0.5-1 mg given SC or IV) and supportive measures to maintain respiration and circulation. Epinephrine (0.3-1 mg, SC or IM) may also be of value in the presence of severe cardiovascular depression or bronchoconstriction. It is not known if pilocarpine is dialyzable.
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