Rostatin Adverse Reactions

The statins have been associated with myalgia, myopathy, myositis, and rhabdomyolysis (see Musculoskeletal Effects under Precautions). Statins can alter liver function tests, and rarely cause hepatitis and jaundice; pancreatitis and hepatic failure have been reported very rarely. Other side­-effects include gastro-intestinal disturbances, sleep disturbance, headache, dizziness, depression, paraesthesia, asthenia, peripheral neuropathy, amnesia, fatigue, sexual dysfunction, thrombocytopenia, arthralgia, visual disturbance, alopecia, and hypersensitivity reactions (including rash, pruritus, urticaria, and very rarely lupus erythematosus-like reactions). In very rare cases, statins can cause interstitial lung disease; if patients develop symptoms such as dyspnea, cough, and weight loss, they should seek medical attention. Statins can cause hyperglycemia and may be associated with the development of diabetes mellitus, particularly in those already at risk of the condition. Proteinuria and very rarely hematuria have been reported.