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Children and adolescents 10 - 17 years: Heterozygous familial hypercholesterolemia (HeFH).
Adults: Used with dietary therapy for hyperlipidemia to reduce elevations in total cholesterol (TC), LDL-cholesterol, apolipoprotein B (apo B) in patients with primary hypercholesterolemia (type IIa including heterozygous familial hypercholesterolemia), mixed dyslipidemia (type IIb), or homozygous familial hypercholesterolemia who have not responded adequately to diet and other appropriate measures. It may be used to reduce the progression of atherosclerosis in patients with elevated total- or LDL-cholesterol concentrations, and also for the primary prevention of cardiovascular disease in those at high risk.
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