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Symptoms: In general, reported signs and symptoms were those resulting from an exaggeration of the active substance's unknown pharmacological effect, i.e., drowsiness and sedation, tachycardia, hypotension and anticholinergic effects.
Overdose could lead to QT-prolongation, patients with pre-existing severe cardiovascular disease may be at an increased risk of the effects of overdose.
Treatment: There is no specific antidote to quetiapine. The prevention of absorption in overdose has not been investigated, gastric lavage can be indicated in severe poisonings and if possible to perform within one hour of ingestion. The administration of activated charcoal should be considered.
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