Sign Out
Symptoms: In clinical studies of originator product, administration of etoricoxib at single doses up to 500 mg and multiple doses up to 150 mg/day for 21 days did not result in significant toxicity. There have been reports of acute overdosage with etoricoxib, although adverse experiences were not reported in the majority of cases. The most frequently observed adverse experiences were consistent with the safety profile for etoricoxib (e.g. gastrointestinal events, renovascular events).
Treatment: Treatment of NSAID toxicity is primarily supportive and symptomatic. In addition to supportive measures, the use of oral activated charcoal may help to reduce the absorption of the NSAID. However, hemodialysis may be necessary in cases of NSAID-induced prolonged or severe renal failure.
