Nephrosteril

Nephrosteril

Manufacturer:

Fresenius Kabi

Distributor:

Zuellig Pharma
Full Prescribing Info
Contents
Amino acids.
Description
NAME AND STRENGTH OF ACTIVE INGREDIENT(S): See table.

Click on icon to see table/diagram/image
Indications/Uses
Balanced supply of protein elements in acute and chronic renal insufficiency as well a during peritoneal and hemodialysis treatment.
Dosage/Direction for Use
For intravenous infusion.
If not otherwise prescribed up to 0.5 g amino acids/kg BW and day ≤ 500 ml per day at 70 kg body weight in acute and chronic renal insufficiency without dialysis treatment. Up to 1 g amino acids/kg BW and day ≤ 1000 ml per day at 70 kg BW in acute and chronic renal insufficiency under dialysis treatment.
Max. dosage: Up to 1.5 g amino acids/kg BW and day ≤ 1500 ml per day at 70 kg body weight. The drop rate should not exceed 20 drops/minute.
Administer calory carriers either before or simultaneously by mouth or parenterally.
Duration: In acute renal insufficiency duration of application is from some days up to maximum of two weeks.
In chronic renal insufficiency without dialysis treatment as well as in acute and chronic renal insufficiency under hemodialysis, hemofiltration, or peritoneal dialysis treatment Nephrosteril can be used until a sufficient oral supply of protein can be again given.
Contraindications
Impaired amino acid metabolism, advanced functional impairment of the liver, severe cardiac insufficiency, hyperhydration, hypokalemia, hyponatremia.
Adverse Reactions
Excessive drop rates may lead to incompatibility such as nausea, chills, and vomiting.
Notes: This solution does not contain electrolytes, observe therefore the blood electrolyte level.
If necessary, supply sufficient potassium in order to ensure the anabolic utilization of amino acids.
Monitor regularly the water electrolyte metabolism as well as the acid-base status and serum urea.
A possibly existing reduction of renal function has to be treated at first by supplying sufficient amounts of water and electrolytes.
The infusion of Nephrosteril may lead to increased production of gastric acid and stress ulcer.
Drug Interactions
The addition of drugs should be avoided, as additives may lead to chemico-physical changes in the amino acid solution and thus to toxic reactions. If drugs have to be given, observe sterility, complete mixture, changes in the solution and general compatibility.
Solution with drugs must not be stored.
Caution For Usage
Do not use if the solution is cloudy or if the container is damaged.
Storage
Store protected from light and not above 25°C.
MIMS Class
Parenteral Nutritional Products
ATC Classification
B05BA01 - amino acids ; Belongs to the class of solutions for parenteral nutrition used in I.V. solutions.
Presentation/Packing
Form
Nephrosteril soln for infusion
Packing/Price
250 mL x 1's;500 mL x 1's
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