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Concomitant use of Naproxen and other non-steroidal anti-inflammatory drugs may increase the risk of renal impairment associated with the use of ACE-inhibitors.
Coadministration of Naproxen and Anti-hypertensives may result in reduced anti-hypertensive effect.
Concurrent use of Naproxen and Cardiac glycosides may exacerbate cardiac failure, reduce GFR and increase plasma glycoside levels.
Coadministration of Naproxen and Corticosteroids may result in increased risk of gastrointestinal ulceration or bleeding.
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