Incompatibilities: Mitoxantrone solution must not be mixed with other drugs in an infusion solution or in a syringe.
Heparin must not be added to Mitoxantrone solution as precipitation may occur.
Do not administer mitoxantrone through the same intravenous line as other drugs.
Special precautions for safe use/handling: When handling mitoxantrone, always wear protective gloves and safety goggles.
If contamination of the eyes, skin or mucous membrane occurs with mitoxantrone, the contact area should immediately be washed thoroughly with water.
If necessary, an ophthalmologist should be consulted. In the course of preparation, application and disposal of contaminated material as well as the decontamination of objects (e.g. sanitary facilities), protective gloves and safety goggles must always be worn. Objects, which have been in contact with Mitoxantrone containing solutions, can be cleaned with a suspension of 5.5 parts by weight of calcium hypochlorite in 13 parts of water. They should be copiously rinsed with water. Objects which were detoxificated with hypochlorite inside are to be reused as containers for Mitoxantrone solutions only after rinsing with diluted acetic acid and subsequent repeated rinsing with water.
Disposal of unused Mitoxantrone-containing solutions and empty vials: Mitoxantrone containing solutions and empty vials should be disposed separately from other drugs according to each current national legal requirement for special waste.
Mitoxantrone Baxter is available on prescription only.
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