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Particularly close medical supervision imperative in the following cases: Diabetic patients with heavily fluctuating blood-sugar values and in strict fasting.
Patients with a hormone-produced tumour of the adrenal medulla (phaeochromocytoma, prior therapy with alpha-blockers necessary).
Patients with restricted hepatic function.
With patients who have psoriasis in their personal or family history, beta-receptor blockers should only be prescribed after careful weighing of the benefits versus the risks.
Effects on ability to drive and use machines: Reactions differing from individual to individual may affect the ability to drive motor vehicles or operate machinery. This applies to a stronger degree at the start of therapy, when switching medications as well as in combination with alcohol.
