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Pregnancy: There are no or limited amount of data from the use of Diosmin and Hesperidin in pregnant women. Animal studies do not indicate teratogenic effect and no harmful effects have been reported to date in humans.
Lactation: It is unknown whether the active substance/metabolites are excreted in human milk. Breastfeeding is not recommended during treatment.
Fertility: Reproductive toxicity studies showed no effect on fertility in male and female rats.
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