Meicelin Caution For Usage

Precautions concerning use: Administration route: This product should be used only by intravenous injection or intravenous drip infusion.
Preparation: 1) In the case of intravenous drip infusion, this product should not be dissolved in distilled water for injection alone (The solution is not isotonic). It should be dissolved in glucose or electrolyte solution.
2) Mixing with aminophylline or pyridoxal phosphate reduces the potency of this product and causes coloration. Therefore, injection by mixing with these drugs should be avoided. Mixing with fursultiamine, thioctic acid, hydrocortisone sodium succinate or cobamamide causes coloration with time. Therefore, after mixing, the mixture should be used immediately.
After dissolution: After reconstitution, the product should be used immediately. Even if the solution has to be stored at room temperature or in a refrigerator, use it within 12 hours or 24 hours, respectively.
At the time of administration: Intravenous administration of this product in a large dose may cause vascular pain and phlebitis. To prevent such reactions, due caution should be exercised in reconstituting the product and also regarding the injection site and injection method, and the injection rate should be as slow as possible.