Sign Out
Symptoms: There is limited experience with overdose of pregabalin. The highest reported accidental overdose of pregabalin was 8,000 mg, and there were no notable clinical consequences.
Treatment: There is no specific antidote for overdose with pregabalin. If indicated, elimination of unabsorbed drug may be attempted by gastric lavage; observe usual precautions to maintain the airway. General supportive care of the patient is indicated, including monitoring of vital signs and observation of the clinical status of the patient. Hemodialysis may be indicated by the patient's clinical state or in patients with significant renal function impairment. Standard hemodialysis procedures result in significant clearance of pregabalin (approximately 50% in 4 hours).
