Lonquex Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing

Concise Prescribing Info

Contents

Lipegfilgrastim

Indications/Uses

Reduction in duration of neutropenia & incidence of febrile neutropenia in adult patients treated w/ cytotoxic chemotherapy for malignancy except chronic myeloid leukaemia & myelodysplastic syndromes.

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Dosage/Direction for Use

SC Adult One 6-mg dose each cycle given approx 24 hr after cytotoxic chemotherapy.

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Overdosage

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Contraindications

Hypersensitivity.

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Special Precautions

Not to be used to increase dose of cytotoxic chemotherapy. Risk of cross-reaction. Discontinue if WBC count is >50 x 10⁹/L; preliminary signs of acute resp distress syndrome occurs. Not to be used in patients w/ chronic myeloid leukaemia, myelodysplastic syndromes or secondary AML. Patients w/ recent history of pulmonary infiltrates or pneumonia; capillary leak syndrome; sickle cell anaemia. Increased risk on hypokalaemia. Reversible thrombocytopenia; leukocytosis; splenomegaly & splenic rupture; aortitis, glomerulonephritis. Regularly monitor platelet count & haematocrit. Carefully monitor spleen size; serum K level; urine. Perform WBC count at regular intervals during therapy. Fructose intolerance. Concomitant use w/ single or combination chemotherapeutic medicinal products causing severe thrombocytopenia. Avoid use during pregnancy. Lactation. Childn & adolescents ≤17 yr.

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Use In Pregnancy & Lactation

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Adverse Reactions

Nausea; musculoskeletal pains. Thrombocytopenia; hypokalaemia; headache; haemoptysis; skin reactions; chest pain.

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Drug Interactions

Concomitant use w/ cytotoxic chemotherapy. Potentiated myelosuppression w/ 5-fluorouracil or other anti-metabolites.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Lonquex detailed prescribing information

Storage

View Lonquex storage conditions for details to ensure optimal shelf-life.

Description

View Lonquex description for details of the chemical structure and excipients (inactive components).

Action

View Lonquex mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Supportive Care Therapy

ATC Classification

L03AA14 - lipegfilgrastim ; Belongs to the class of colony stimulating factors. Used as immunostimulants.

Thai FDA Category

Presentation/Packing

Form

Lonquex soln for inj 6 mg/0.6 mL

Packing/Price

0.6 mL x 1's

Lonquex

Manufacturer:

Teva Pharma

Distributor:

Pacific Healthcare

Marketer:

Pacific Healthcare