Kidmin Dosage/Direction for Use

Chronic Renal Failure: Peripheral vein infusion: The usual adult dosage is 200 mL per day, infused via a peripheral vein. The usual infusion rate in adults is 100 mL over 60 minutes (approx. 25 drops per minute) and it should be slowly infused in children, the elderly and seriously ill patients. The dosage may be adjusted according to the patient's condition, body weight and age. When administered during hemodialysis, it should be infused via the vein side injection port of dialysis circuit starting 90-60 minutes before the end of hemodialysis therapy. Regarding calories, more than 1500 kcal per day is recommended to be provided for the efficiency of amino acid utilization.
Central vein infusion: The usual adult dosage is 400 mL per day, Infused via a central vein by total parenteral nutrition. The dosage may be adjusted according to the patient's condition, body weight and age. More than 300 kcal of non-protein calories should be administered per 1 g of nitrogen (100 mL of this product) for the efficiency of amino acids utilization.
Acute Renal Failure: The usual adult dosage is 600 mL per day, infused via a central vein by total parenteral nutrition. The dosage may be adjusted according to the patient's condition, body weight and age. More than 300 kcal of non-protein calories should be administered per 1 g nitrogen (100 mL of this product) for the efficiency of amino acid utilization.
Precautions in dosage and administration: Since it has been reported that hyperammonemia or consciousness disorder occurred when an amino acid injection for renal failure was administered as the sole amino acid source, discontinue use of this product immediately when abnormalities including slow reaction to being called or greetings or reduction in spontaneous motor activity or expressing opinions are observed.
Since azotemia or metabolic acidosis may be enhanced in case of inadequate administration of calories, the patients must be carefully observed during administration. If abnormalities are found, institute appropriate measures such as withdrawing administration.