Initial therapy for serious infections caused by bacterial susceptible to kanamycin. Treatment of bacterial infections of the gastrointestinal tract. Treatment of urinary tract infections caused by Proteus vulgaris, Escherichia coli, Staphylococcus spp., and Neisseria gonorrhoeae (gonorrhea). Treatment of respiratory tract and intrathoracic infections caused by Staphylococcus spp., Streptococcus pneumoniae, and Haemophilus influenzae. Relief of inflammation of the skin or localized bacterial infections, including inflammatory conditions of the ear, nose, and eyes.