Contact of the undiluted concentrate with plasticized polyvinyl chloride (PVC) equipment or devices used to prepare solutions for infusions is not recommend. In order to minimize patient exposure to the plasticizer DEHP [di -(2 ethylhexyl)phthalate], which may be leached from PVC infusion bags or sets, diluted INTAXEL solutions should preferably be stored in bottles (glass, polypropylene) or plastic bags (polypropylene, polyolefin) and administers through polyethylene lined administration sets.
INTAXEL should be administered through as in line with a microporous membrane not greater than 0.22 microns.
Use in Children: The safety and effectiveness of Paclitaxel in children has not been established.
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