Paclitaxel Injection USP (INTAXEL) is a clear colorless to slightly yellow viscous solution. It is supplied as a non-aqueous solution intended for dilution with a suitable parenteral fluid prior to intravenous infusion. INTAXEL is available as 5 mL, 17 mL, 43.4 mL and 50 mL multi dose vials. Each mL of sterile solution contains 6 mg Paclitaxel USP, 527 mg of Polyoxyl 35 Castor Oil USNF and 49.7% (v/v) Dehydrated Alcohol USP.
Paclitaxel is a product with antitumour activity. The chemical name for Paclitaxel is 5β,20-epoxy- 1,2α,4,7β,10β,13α-hexahydroxytax-11-en-9-one4,10-diacetate2-benzoate13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine.
Paclitaxel is a white to off white crystalline powder with the empirical formula C47H51NO14
and a molecular weight of 853.9. It is highly lipophilic, insoluble in water, soluble in alcohol and melts at around 216-217 °C.
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