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Pharmacotherapeutic group: Immune sera and immunoglobulins: anti-D (Rh) immunoglobulin. ATC code: J06BB01.
Pharmacology: Igamad is a solution for injection of human anti-D (Rh) immunoglobulin that contains specific antibodies (IgG) against the D (Rh) antigen of human erythrocytes and that has been subjected to a pasteurisation process.
Measurable levels of antibodies are obtained approximately 20 minutes after human anti-D (Rh) immunoglobulin i.m. injection. Peak serum levels are usually achieved 2 to 3 days later.
The half-life in the circulation of individuals with normal IgG levels is 3 to 4 weeks.
IgG and IgG-complexes are broken down in cells of the reticulo-endothelial system.
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