Gansulog Dosage/Direction for Use

Insulin glargine is a long-acting insulin administered by SC injection.
Recommended dose: Patients ≥ 18 years of age: Diabetes mellitus, type 1: SC dose: Initial dose: Approximately one-third to one-half of the total daily insulin requirement administered once daily.
Diabetes mellitus, type 2: SC dose: Initial basal insulin dose: 0.2 units/kg once daily; up to 10 units/day. Adjust dosage according to patient response.
Patients under 18 years of age: No data are available for patients under 18 years of age.
Special populations: Renal impairment: The safety and efficacy of Gansulog have not been established in Renal impairment population. No data are available. However, Insulin requirement may be reduced due to changes in insulin clearance or metabolism.
Hepatic impairment: The safety and efficacy of Gansulog have not been established in Hepatic impairment population. No data are available. However, Insulin requirement may be reduced due to changes in insulin clearance or metabolism.
Dosage adjustment: Dosage must be titrated to achieve glucose control and avoid hypoglycemia.
Administration: Insulin glargine should only be administered subcutaneously.
Do not use if solution is viscous or cloudy; use only if clear and colorless with no visible particles. Insulin glargine should be administered once daily at the same time each day. Do not dilute or mix insulin glargine with any other insulin formulation or solution.
Injection sites should always be rotated within the same region in order to reduce the risk of lipodystrophy and cutaneous amyloidosis.
Please bring Gansulog to room temperature before use and follow the injection steps described as follows: (1) Check the insulin to make sure it is clear and colorless. Do not use Gansulog if it is colored or cloudy, or if the patient sees particles in the solution.
(2) Gansulog should be used with GanleePen insulin delivery device only (the reusable pen), please read the GanleePen's medical device instruction manual before use.
(3) Gansulog is injected under the skin (subcutaneously) of the upper arm, thigh, or stomach area (abdomen). Wipe the skin with an alcohol swab to clean the injection site. Let the injection site dry before the patient injects the dose. Injection sites must be rotated within a given injection area from one injection to the next.
(4) Pinch the skin of the injection site with the fingers and puncture the needle. After the pusher is pushed to the end, keep the needle under the skin for a few seconds to ensure that the correct dose is injected, then pull out the needle, and gently press the injection site with the sterile cotton ball for a few seconds, but do not rub the injection site to avoid damage to the subcutaneous tissue or cause the exudation of Gansulog.