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FOSFOMYCIN is antibiotic, first discovered in 1967 in a culture of Streptomyces fradiae, which was isolated from a Spanish soil sample. It is quite different from other antibiotics in that it has a very simple and unique chemical structure.
Each vial of FOSMICIN FOR I.V. USE contains 2 g or 4 g (potency) of fosfomycin sodium, a white crystalline powder for injection.
pH and Osmotic Pressure Ratio: See Table 1.
Click on icon to see table/diagram/imageWhen 2 g of FOSMICIN FOR I.V. USE was dissolved in 20 and 100 ml each of distilled water for drip, physiological saline and 5% glucose solution and the resultant solutions were preserved for 7 days at 25°C and 40°C, there were almost no changes in the potency, pH or appearance, indicating that the solutions are stable.
The same results were obtained with 4 g of FOSMICIN FOR I.V. USE when tested by the previously-mentioned method.
Molecular Formula: C3H5Na2O4P.
Molecular Weight: 182.02.
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